Management of anticoagulant therapy during pregnancy in patients with prosthetic heart valves.
نویسندگان
چکیده
We describe two patients with Starr-Edwards mitral valve replacements who underwent pregnancy on oral anticoagulants and who were successfully delivered of live babies. The literature on pregnancy with prosthetic heart valves is reviewed. It is suggested that properly controlled oral anticoagulation should be continued until the onset of labour; the anticoagulant effect should then be reversed by an intravenous infusion of fresh-frozen plasma and the patient maintained on intravenous heparin injections six-hourly. Oral anticoagulants should be restarted immediately after delivery and the heparin withdrawn only when their effect has been re-established.
منابع مشابه
Pregnancy Outcome with Intracytoplasmic Sperm Injection Method in a Woman with Prosthetic Heart Valves
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متن کاملAnti-Coagulation During Pregnancy in Women with Mechanical Heart Valves: A Prospective Study
متن کامل
[Pregnancy in women with a mechanical heart valve. Review of the literature].
AIM To define therapeutic ways to manage obstetrics at an optimal level for a patient carrying a mechanical prosthetic heart valve. METHOD From a review of literature and documented cases, we propose an obstetrical and cardiological management scheme for pregnant patients carrying a mechanical prosthetic heart valve. We deal successively with the preventive (anticoagulation) and curative trea...
متن کاملProsthetic heart valve selection in women of childbearing age with acquired heart disease: a case report.
BACKGROUND The problem of prosthetic heart valve selection in fertile women with acquired heart defects remains crucial in modern cardiology. Mechanical heart valves require lifelong indirect anticoagulant therapy, which has significant fetal toxicity and is unacceptable for women planning pregnancy. Bioprosthetic heart valves are the best choice for fertile women; however, their durability is ...
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ورودعنوان ژورنال:
- Thorax
دوره 26 2 شماره
صفحات -
تاریخ انتشار 1971